南西奥

Enancio公司最近由Ilumina获取专有无损数据压缩技术专为基因组数据设计

The compression technology will first be integrated into DRAGEN BCL conversion, giving users the option to produce compressed fastq files that are 5x smaller than fastq.gz^一号.

NextSeq1000/2000上提供压缩技术,从仪表上生成压缩快q文件Stay tuned for future DRAGEN releases that will include lossless genomic compression of fastq files as part of BCL Conversion

NGS工作流期间,您可任选启动压缩生成压缩快q.ora文件Fastq.ora files can be decompressed on the fly for mapping and downstream analysis and will soon be directly ingested by DRAGEN.The integration of compression within DRAGEN BCL conversion streamlines the workflow, as shown in the figure below:

光素压缩技术

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Before Enancio's acquisition: compression as a standalone software.压缩是一个额外步骤

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压缩技术输出新压缩快二叉文件格式:快q.ora文件格式可存储共享,以便节省存储费用并减少文件传送时间所有压缩文件都可用免费解压缩软件.

fastq.ora文件可解压缩飞线映射和下游分析,不久将直接由DRAGEN取用

235GB原快克文件可以通过gzip压缩为55GBThe data footprint is further reduced to 11 GB with the Illumina compression technology².

fastq文件和BAM或CRAM文件通常为不同目的存储However, fastq.ora files enable you to store a compressed copy of your raw data with a preserved MD5 sum and smaller footprint than the corresponding CRAM file.

DRAGEN系统已生成 CRAM压缩bAM文件Once the Enancio compression is integrated into DRAGEN, you will be able to compress Fastqs and BAMs to fastq.ora and CRAM respectively.

压缩使用完全可选DRAGEN users remain free to adopt the storage strategy they want: activate the conversion to Illumina fastq compressed file format and store these files, disable the conversion to Illumina compressed file format fastq.ora and store fastq.gz, or store BAM or CRAM files.

压缩技术将无缝融入DRAGEN工作流

此外 曾免费解压缩软件is installed, a simple command can be used to directly pipe the output of decompression on the fly into a wide range of popular mapping tools such as BWA³星际大战⁴和波台⁵.

光照快速压缩文件可共享上头解压缩软件可免费获取Once the free decompression software is installed, a simple command can be used to directly pipe the output of decompression on the fly into a wide range of popular mapping tools such as BWA³星际大战⁴和波台⁵.